Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax): Evaluation of Measurement Performance
نویسندگان
چکیده
Background: Clinical trials of primary axillary hyperhidrosis (AHH) require rigorous measurement AHH severity from the patient’s perspective. Previously, we reported conceptualization and item content development for Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax) scale. Objective: To evaluate psychometric performance estimate clinically meaningful change scores HDSM-Ax in a Phase IIb clinical study sofpironium bromide gel AHH. Method: was analyzed trial response data using two paradigms: Classical Test Rasch Measurement Theories (CTT; RMT). were estimated anchor-based methods global summary questions Score (HDSS). Results: satisfied CTT RMT criteria as fit-for-purpose outcome measure trials. Within-person analyses indicated 1-point score (range, 0–4) represents severity. Conclusion: is well-defined reliable A meaningful. J Drugs Dermatol.20(4):410-418. doi:10.36849/JDD.5569
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ژورنال
عنوان ژورنال: Journal of Drugs in Dermatology
سال: 2021
ISSN: ['1545-9616']
DOI: https://doi.org/10.36849/jdd.5569